Manchester City look to have been dealt another defensive injury blow after Nathan Ake came off in the 3-1 FA Cup win over Plymouth.Ake was substituted at half-time in the fifth-round tie at the Etihad Stadium, being replaced by Ruben Dias.And City boss Pep Guardiola, who has the likes of John Stones and Manuel Akanji on the sidelines, said in his post-match press conference: "Now again we have central defenders out. I think we are going to miss Nathan."

Manchester City look to have been dealt another defensive injury blow after Nathan Ake came off in the 3-1 FA Cup win over Plymouth.Ake was substituted at half-time in the fifth-round tie at the Etihad Stadium, being replaced by Ruben Dias.And City boss Pep Guardiola, who has the likes of John Stones and Manuel Akanji on the sidelines, said in his post-match press conference: "Now again we have central defenders out. I think we are going to miss Nathan."