Harry Kane looks a major doubt for England's friendly against Wales after missing training on the eve of the game.Thomas Tuchel's side welcome their neighbours to a sold-out Wembley on Thursday before attention turns to Tuesday's World Cup qualifier in Latvia.Kane seems set to miss the first game of October's double-header, having sat out training on Wednesday along with uncapped Bayer Leverkusen defender Jarell Quansah.

Harry Kane looks a major doubt for England's friendly against Wales after missing training on the eve of the game.Thomas Tuchel's side welcome their neighbours to a sold-out Wembley on Thursday before attention turns to Tuesday's World Cup qualifier in Latvia.Kane seems set to miss the first game of October's double-header, having sat out training on Wednesday along with uncapped Bayer Leverkusen defender Jarell Quansah.