The findings of a major review that concluded that medical treatment in children's gender care has been based on weak evidence has shone a spotlight on the need to "exercise extreme caution" in this area, the Prime Minister has said.The Cass Review's final report, published on Wednesday, said children have been let down by a lack of research and evidence on the use of puberty blockers and hormones, in a debate that it said has become exceptionally toxic.The recommendations in the lengthy and lon

The findings of a major review that concluded that medical treatment in children's gender care has been based on weak evidence has shone a spotlight on the need to "exercise extreme caution" in this area, the Prime Minister has said.The Cass Review's final report, published on Wednesday, said children have been let down by a lack of research and evidence on the use of puberty blockers and hormones, in a debate that it said has become exceptionally toxic.The recommendations in the lengthy and long-awaited report have prompted NHS England, which had already stopped puberty blockers being given to under-16s, to announce a review into the use of hormones.